A pilot study on effect of intravenous iron sucrose on oxidative stress and antioxidant status of pregnant women with iron deficiency anemia

Objectives: Iron deficiency anemia (IDA) is the most common nutritional among pregnant women in India. can be supplemented orally or intravenously to treat IDA. Intravenous supplementation of iron risky as there more possibility for production free circulation. The role generation radicals and thereby oxidative stress well known. present study tends evaluate antioxidant status intravenous sucrose treated women. Materials Methods: This prospective was conducted ACS Medical College Hospital, Chennai. Twenty with moderate IDA (Hb: 7–9.9 g/dl) were included study. Blood samples collected before after treatment measure antioxidants such reduced glutathione, catalase superoxide dismutase, lipid peroxidation marker malondialdehyde. Results: In study, plasma malondialdehyde levels increased significantly sucrose. No significant alterations observed glutathione activities dismutase. Conclusion: infusion associated evidenced by antenatal Hence, during infusions considered.